Rossett School in Harrogate has confirmed a second year 12 pupil has tested positive for coronavirus.
A further 24 students in the year who were in prolonged contact with the pupil will self-isolate.
In an e-mail to parents, headteacher Helen Woodcock said the school remained open and other pupils should attend as normal.
Ms Woodcock said a “deep enhanced cleaning” of the sixth form centre had taken place.
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Her email added:
“In line with national guidance I have today contacted the Department for Education and North Yorkshire County Council and we are following their guidance, along with that provided by Public Health England.
“A risk assessment has been completed to identify all individuals who have been in close prolonged contact with the student (24 Year 12 students) and they have received a phone call and a letter home today to inform them of the period of self-isolation.”
Another year 12 pupil at the school was confirmed to have Covid on Monday.
Meanwhile, 16 cases of coronavirus were confirmed in the Harrogate district yesterday.